KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCTD10
All Species:
31.82
Human Site:
Y250
Identified Species:
77.78
UniProt:
Q9H3F6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3F6
NP_114160.1
313
35432
Y250
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Chimpanzee
Pan troglodytes
XP_001137814
324
36866
Y259
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Rhesus Macaque
Macaca mulatta
XP_001105476
316
35827
Y251
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Dog
Lupus familis
XP_851671
287
32371
G240
Y
E
A
Q
D
G
R
G
P
D
N
A
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q922M3
315
35683
Y250
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Rat
Rattus norvegicus
Q7TPL3
315
35726
Y250
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3E8
314
36014
Y251
E
F
P
E
A
R
I
Y
E
E
T
L
N
V
L
Frog
Xenopus laevis
Q5EAX2
319
36469
Y250
E
F
P
E
A
R
I
Y
E
E
T
L
N
V
L
Zebra Danio
Brachydanio rerio
NP_998643
313
35524
Y250
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797819
336
37301
L284
E
F
P
E
A
R
I
L
E
E
T
L
N
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
99
91.6
N.A.
97.7
97.7
N.A.
N.A.
71.3
70.2
94.5
N.A.
N.A.
N.A.
N.A.
58.3
Protein Similarity:
100
96.5
99
91.6
N.A.
98.7
99
N.A.
N.A.
82.1
80.5
97.4
N.A.
N.A.
N.A.
N.A.
69.9
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
N.A.
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
90
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
90
10
0
90
0
0
0
0
90
90
0
0
0
0
10
% E
% Phe:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
90
0
0
0
0
0
0
60
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
90
10
10
90
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
90
0
0
% N
% Pro:
0
0
90
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
90
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
90
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _